Image of Guardian™ Connect system, i-Port Advance™
injection port and InPen™ smart insulin pen

Smart MDI: CGM + smart insulin pen system

For people who manage their diabetes with insulin injections, the Smart MDI system can help relieve the physical and mental effort required, by using an ecosystem of smart-enabled technology devices, to help make life a bit easier.

The Smart MDI system includes a continuous glucose monitor (CGM), an injection port, and smart insulin pen.

For people living with type 1 or type 2 diabetes, we have tools to help you stay ahead.

Discover more today!

Ask more of your CGM

See how much more it can do as part of a system

Combine these three powerful tools that can help you stay ahead of diabetes

Connect system

Image of the Guardian™ Connect system showing a sensor and smart phone with app screen

Do high sugar levels have you down?

Get ahead of your highs
The only continuous glucose monitor (CGM) that can predict a high or low up to an hour in advance.*

  • Easy-to-use app
  • Small sensor & transmitter
  • Automatic uploads

Learn how different foods & activities affect your sugars in real time

smart insulin pen

Image of the InPen™ smart insulin pen system showing a smart phone with app screen, bluetooth symbol and blue InPen with the cap off

Did you forget to dose?

The right dose at the right time
Bluetooth® enabled smart pen that does the math and logs doses for you.

  • Calculates insulin doses
  • Offers dose reminders
  • Delivers half unit doses
  • Monitors insulin temperature

Get personalized dosing recommendations

i-Port Advance
injection port

Image of the i-Port Advance™ injection port

Want to reduce needle pokes?

It takes the shots for you
Deliver your insulin injections without having to puncture your skin for each shot.

  • 1 poke every 3 days
  • Simple to apply and easy to use

93% reduction in needle pokes**

Image of Medtronic Smart MDI products - Guardian™ Connect, InPen and i-Port Advance™ injection port

Get started with Smart MDI!

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Life with InPen and the Guardian Connect CGM—Sarah’s Story

Play button to watch Sarah video Image of Sarah walking her dog


Lives with type 1 diabetes and was diagnosed as a young adult.

Meet Sarah

Compensated for her time. Thoughts and opinions are her own.

* Alerts must be set to receive predictive alerts
** Based on 150 injections per month versus 10 insertions per month
† Proper settings and user interaction required, including manual logging of rapid-acting insulin given by other means. WARNING: not doing so may lead to hypoglycemia, which could result in serious injury or death.

The Bluetooth® word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Medtronic is under license.

Important Safety Information: Guardian Connect CGM System
The Guardian Connect system requires a prescription and is indicated for continuous or periodic monitoring of glucose levels in the interstitial fluid under the skin, in patients (14 to 75 years of age) with diabetes mellitus. The system is intended to complement, not replace, information obtained from standard blood glucose monitoring devices, and is not recommended for people who are unwilling or unable to perform a minimum of two meter blood glucose tests per day, or for people who are unable or unwilling to maintain contact with their healthcare professional. The system requires a functioning mobile electronic device with correct settings. If the mobile device is not set up or used correctly, you may not receive sensor glucose information or alerts. For complete details of the system and its components, including warnings, contraindications, and precautions, please consult the user guides and important safety information.

Important Safety Information: InPen
The InPen is a home- use reusable pen injector for single- patient use by people with diabetes under the supervision of an adult caregiver, or by a patient age 7 and older for the self- injection of a desired dose of insulin and for calculating an insulin dose or carbohydrate intake based on user entered data. A healthcare professional must assist in dosage programming of the device prior to use, based on various patient- specific criteria and targets. The InPen requires a prescription. For additional product and safety information, please consult the Instructions for Use and

Safety Information: i-Port Advance injection port
i-Port Advance injection port is indicated for patients who administer or receive multiple daily subcutaneous injections of physician prescribed medications, including insulin. The device may remain in place for up to 72 hours to accommodate multiple injections without the discomfort of additional needle sticks. i-Port Advance injection port may be used on a wide range of patients, including adults and children. For more, please see important safety information.